Cellular, Molecular and Genetic Medicine

Applications for the Fall 2025 semester are now open!

Exciting news awaits you! The CMGM Postdoc Association has officially opened applications for its coveted travel grant award. From July 15 to September 15, 2025, you can apply for one of two $750 grants designed to support your research projects and foster your professional growth. This grant is tailored for you! It provides the financial backing needed to explore new ideas, network with fellow scholars, and elevate the quality of research.

For more details, contact ushasaraswat.mahawar@vcuhealth.org

About Travel Grant

The CMGM Postdoctoral Travel Grant Program has been established to support and promote the dissemination of research and scholarly activities by offering travel grants to postdoctoral fellows in the Department of Cellular, Molecular, and Genetic Medicine at Virginia Commonwealth University. This grant is designated solely for expenses related to participation in conferences or other suitable presentation venues. Awards will be allocated without consideration of quotas or distribution across various fields and programs. This travel grant is intended to provide additional support rather than replacing the PI's existing funding.   It is important to note that funding is limited, and postdoctoral fellows applying for this program are not guaranteed financial support.

Eligibility:

The postdoctoral fellow who receives funding from this travel grant program must present the presentation. Travel must occur between August 1 and December 31 for the fall semester applications and between February 1 and June 30 for the spring semester applications. Additionally, the postdoctoral fellow must not have received this award in the last year.

Funding: The maximum award is $750. Two prizes, each worth $750, will be given per semester. This amount is subject to change based on funding.

For more information, please contact ushasaraswat.mahawar@vcuhealth.org

Applications Now Open for the Dr. Robert F. Diegelmann Best Postdoc of the Year Award

The CMGM department is excited to announce that applications for the prestigious "Dr. Robert F. Diegelmann Best Postdoc of the Year Award" are now being accepted. Applications for the academic year 2025-26 will be accepted until August 30, 2025. Postdoctoral researchers who have made significant contributions in mentoring, collaboration, and research impact are encouraged to apply. 

For more information on the application process and eligibility criteria, reach out to  alexandra.gonsiewski@vcuhealth.org.

Don't miss this opportunity to be recognized for your outstanding contributions to science and research. Apply now!

About the award:

In 2025, the "Dr. Robert F. Diegelmann Outstanding Postdoc of the Year Award" was established to provide prestigious recognition for the exceptional contributions of postdoctoral researchers within the CMGM department. Dr. Diegelmann, PhD, is a retired distinguished career and emeritus professor from the former Department of Biochemistry and Molecular Biology.

This award recognizes the hard work, dedication, and innovative research conducted by postdocs, who are often underappreciated for scientific advancements. By celebrating their achievements, the award not only boosts the morale of the recipients but also inspires other researchers to strive for excellence.

Recognizing postdocs' efforts in mentoring, collaboration, and research impact fosters a supportive and collaborative research environment. This award serves as a testament to the significant role postdocs play in advancing knowledge and driving scientific progress. Ultimately, it underscores the importance of nurturing and valuing the next generation of researchers, ensuring a vibrant and dynamic future for the scientific community.

Eligibility Criteria:

1. Postdoctoral Researchers: The award is open to all postdoctoral researchers associated with the CMGM department.
2. Research Contributions: Candidates must have made significant contributions to their field of research, demonstrated through publications, presentations, or other scholarly activities.
3. Mentorship and Collaboration: Candidates should have shown excellence in mentoring junior researchers and collaborating with peers.

Nomination Process

1. Application Period: TBD (every year)
2. Submission Requirements: Applicants must submit a detailed CV (covering last year only).  A one-page document outlining their future goals and explaining how this award aligns with those objectives, and a letter of recommendation from the mentor.
3. Review Committee: A committee of professors will review the applications and select the finalists.

Evaluation Criteria

1. Research Impact: The significance and impact of the candidate's research on their field.
2. Innovation: The originality and creativity of the candidate's research.
3. Mentorship: The candidate's contributions to mentoring and supporting junior researchers.
4. Collaboration: The candidate's ability to collaborate effectively with other researchers.
5. Active participation in the events of the postdoc association.

Award Ceremony

1. Announcement: TBD (every year).
2. Prize: The award will include a certificate and a monetary prize.

Past recipients of the Awards.

Recipients of Travel Award Fall Semester 2025

• Anna Kovilkath
• Usha Mahawar

 Recipient of the Robert F. Diegelmann Award for outstanding postdoctoral fellow

• Usha Mahawar (2025)

PI: Xiang-Yang Wang, Ph.D., Professor

Education: I earned my Master's and Ph.D. in medicine and veterinary medicine, specializing in parasitology and immunology, from Miyazaki University, Japan.

Research: Acetaminophen (APAP) overdose remains a leading cause of acute liver failure, with limited treatment options beyond N-acetylcysteine (NAC). This study investigates the role of fatty acid oxidation (FAO), specifically through carnitine palmitoyltransferase 1A (CPT1A), as a novel protective and regenerative mechanism in APAP-induced liver injury. Using hepatocyte- and macrophage-specific CPT1A knockout mouse models, we explore how FAO modulates cytotoxic stress, immune responses, and liver regeneration. We also evaluate a novel AMP-activated protein kinase (AMPK) agonist to therapeutically enhance fatty acid oxidation (FAO) activity. These findings aim to uncover new metabolic strategies for treating APAP toxicity and improving liver recovery outcomes.

About me: When I’m not in the lab, you can find me hiking local trails, capturing nature through photography or experimenting with new recipes in the kitchen. I find that time outdoors fuels my creativity and brings balance to my life. I also enjoy science communication and mentoring, which help me stay connected and inspired both inside and outside the lab.

Contact: panian.ahmadi@vcuhealth.org

PI: Xiang-Yang Wang, Ph.D., Professor

Education: Ph.D. in Biomedical Science (Cancer Biology) from the University of Iowa.

Research: My overall research interests are in finding new strategies to enhance immunotherapy response rates and improve patient outcomes in cancer. My graduate research focused on the impact of in situ immunization with a virus-like particle containing a TLR9 agonist on tumor-specific CD8+ T cell effector function and exhaustion development. My postdoctoral project focuses on evaluating the impact of a novel fusion molecule on dendritic cell activation, T cell priming and effector function, and direct tumoricidal activity. The fusion molecule consists of 3 parts: a flagellin-derived NF-κB-stimulating sequence, the molecular chaperone Grp170, and interleukin-24/melanoma differentiation-associated gene-7 (IL24/MDA-7), a cytokine capable of direct tumoricidal activity. By combining these 3 components, we hope to establish a therapy that promotes immunogenic cell death, prevents tumor escape and metastasis, and increases immune checkpoint blockade responsiveness to generate a durable anti-tumor immune response.

About me: When I am not in lab, I enjoy reading a good book or watching a TV show or movie to unwind. I also enjoy watching sports, especially the Boston Bruins and New England Patriots. Other hobbies of mine include painting, drinking coffee, and going on a nice nature walk.

Contact: Travis.Fischer@vcuhealth.org

PI: Paul B. Fisher, M.Ph., Ph.D., FNAI, Professor

Education: Ph.D. in Life Sciences, with a specialization in Cancer Biology, National Institute of Technology, Rourkela, India.

Research:

My research focuses on developing novel therapeutic strategies for glioblastoma (GBM), with
an emphasis on oncolytic virotherapy and cancer immunotherapy. My work involves
developing and evaluating conditionally targeted viral vectors designed to selectively target tumor cells and enhance therapeutic efficacy. In addition, my research explores natural killer (NK) cell-based therapies and their ability to target GBM, including strategies to improve NK-cell infiltration into the tumor microenvironment. Overall, my work aims to develop innovative combination approaches that can overcome therapeutic resistance and improve treatment outcomes for patients with aggressive brain tumors.

About me:

Outside the laboratory, I enjoy playing badminton and traveling. I like exploring new places, experiencing different cultures, and spending time with family and friends. I also enjoy helping others and building meaningful connections with people. These interests help me maintain a healthy balance between my scientific work and personal life.

Contact: Sayantan.ghosh@vcuhealth.org

PI: Carlos Escalante, Ph.D., Associate Professor

Education: Ph. D. in Biological Sciences, Experimental Biology, at the Institute of Chemical Biological Investigations of the Michoacana University of San Nicolas de Hidalgo, Mexico.

Research: My research is on the use of adeno-associated virus (AAV) as vectors in gene therapy. Our lab uses structural and biochemical assays to ascertain the role of the Rep proteins and their interactions with the viral capsid throughout the life cycle of the virus. I am currently studying the mechanism of DNA packaging by Rep proteins as one central issue in the implementation of AAVs is the presence of empty viral capsids. By growing our understanding of this mechanism, we can aim to improve its efficiency and AAV genetic therapy as a whole. 

About me: I'm from Mexico and have been working at VCU for three years. When I'm not in the lab, I enjoy walking the city trails, scrapbooking, and knitting. I also love reading books and enjoying the sounds of birds singing. I struggle with socializing because I need to improve my English, but if you'd like to chat about life, I'd be happy to listen.

Contact: Karen.Hernandez@vcuhealth.org

PI: Xiang-Yang Wang, Ph.D., Professor

Education: Ph.D. in clinical discipline of Chinese and Western integrative medicine, Peking University

Research: My primary research focus is on lysosome function mediated by the bioactive sphingolipid metabolite ceramide in the context of glomerular injury and sclerosis. As I progressed in my career, I found myself increasingly drawn to cancer biology and oncology, and particularly the roles of bioactive sphingolipid metabolites. My research interests now are on the connection between metabolic disorders and pancreatic cancer, the most lethal cancer with an extremely poor survival rate.

About me: I enjoy exploring new experiences together with my family.

Contact: dandan.huang@vcuhealth.org

PI: L. Ashley Cowart, Ph.D., Professor

Education: Ph.D. in human and molecular genetics

Research: My research focuses on elucidating the role of non-canonical sphingolipids in hepatocellular carcinoma (HCC), with particular emphasis on how these atypical lipid species contribute to tumor progression and liver metabolic dysregulation. Using hepatocyte-specific genetic models and lipidomics, I investigate the functional impact of altered sphingolipid biosynthesis pathways. A central aim is to understand how enzymes like SPTLC3 drive the production of non-canonical sphingolipids and influence oncogenic signaling. This study aims to identify novel metabolic vulnerabilities in HCC that may inform future therapeutic strategies.

About me: When I'm not in the lab, you can usually find me running after my energetic toddler — being a mom of three keeps me constantly on my toes! While it’s tough to find time for traditional hobbies, I enjoy winding down with a good TV show or scrolling through YouTube. These simple moments help me recharge and bring a bit of balance to my busy life.

Contact: maryam.jamil@vcuhealth.org

PI: L. Ashley Cowart, Ph.D., Professor

Education: Ph.D. in human genetics, Virginia Commonwealth University; M.S. in human genetics, Virginia Commonwealth University; B.Sc. in biotechnology, Manipal University

Research: My research investigates how aromatase inhibitors (AIs), commonly used in hormone receptor-positive breast cancer, contribute to atherosclerosis and cardiovascular risk. I utilize in vitro and in vivo models to investigate AI-induced alterations in vascular cell behavior, plaque progression, and macrophage function. A major focus is on the role of sphingolipids, particularly SPTLC3-derived species, in mediating these effects. This work bridges basic lipid biology with translational cardio-oncology, aiming to uncover mechanisms of AI-associated cardiotoxicity and identify potential therapeutic targets.

About me: When I'm not in the lab, you can usually find me rock climbing, reading or going on walks with my husband and our two dogs. I also enjoy quiet evenings, cuddled up with a good book and our cat, mTOR. These hobbies help me unwind and maintain a healthy work-life balance.

Contact: anna.kovilakath@vcuhealth.org

PI: Brian (Binks) Wattenberg, Ph.D., Professor

Education: Ph.D. in biochemistry and molecular biology, Virginia Commonwealth University

Research: My research focuses on understanding the mechanisms by which serine palmitoyltransferase (SPT), the first and rate-limiting enzyme in the de novo sphingolipid biosynthesis pathway, is regulated by its regulatory subunit, the ORMDLs. I am especially interested in the functional implications of ORMDL-based regulation of SPT in central nervous system (CNS) myelinating glial cells, such as oligodendrocytes, and skin keratinocyte cells.

About me: When I’m not immersed in my lab, you’ll find me on exciting shopping escapades or exploring the natural world’s beauty. I love unleashing my creativity through crafting. As a dedicated Reiki energy healing practitioner, I channel positive vibes and tranquility. My passion for crystals and gemstones inspires me, and I find joy in the soothing powers of sound and aroma healing. Embracing every moment, I’m all about adventure and spiritual growth!

Contact: I would love to connect! Feel free to reach out via email at ushasaraswat.mahawar@vcuhealth.org.

PI: Dr. Paul B. Fisher, M.Ph., Ph.D., FNAI, Professor

Education: Ph.D in Cancer Biology

Research: My research focuses on studies designed to define precisely how established and newly discovered molecular determinants control cancer progression and the process of metastasis.  My specific focus will be define the role of epigenetic memory in response to therapy and how it contributes to therapy resistance in breast cancer.

About me: Beyond the lab, I am an avid cricket enthusiast — both a passionate follower and an occasional player. I enjoy experimenting in the kitchen and discovering new cuisines through cooking. I love traveling to scenic destinations and often find relaxation in long drives. I take pride in helping others and naturally connect with people, building meaningful relationships with ease. Quality time with my family is central to my life and keeps me grounded.

Contact: ShahidMaqbool.Mir@vcuhealth.org

PI: Dr. Kaustubh Datta, Ph.D., Professor

Education:Ph.D.

Research: My research aims to decipher the role of prostate cancer and tumor microenvironment interaction in promoting disease progression and therapy resistance. A thorough understanding of this process will help to identify appropriate targets for drug development, which can prevent the metastatic dissemination of castration resistant prostate cancer and thus can protect the lives of the patients from this lethal disease.

About me: Dedicated scientist and a devoted mother. I chose to live my life with gratitude and compassion. I love spending time with my family, and when I am not working, you can find me cooking or relaxing

Contact: juhi.mishra@vcuhealth.org

Contact: Pritam.Roy@vcuhealth.org

PI: Can Senkal, Ph.D., Assistant Professor

Education: Ph.D. in clinical and translational research, Virginia Commonwealth University; B.S., George Washington University

Research: My research focuses on the roles of sphingolipids in the onset and progression of cancer and other diseases. One of my projects investigates the molecular regulation of ceramide synthases in the context of cancer, with the goal of developing novel chemotherapeutics that target the generation of ceramide. My second project aims to understand the regulation of glycosphingolipid generation in cancer and works to elucidate the mechanistic underpinnings of glycosphingolipid depletion in colon, ovarian and cervical cancers.

About me: When I’m not in the lab, I spend time walking around the city or hiking out in nature.

Contact: alexandra.straus@vcuhealth.org

PI: Sumitra Deb, Ph.D., Professor

Education: Ph.D. in Biomedical Science, University of Delhi, Delhi, India 

Research: I am currently working on the p53 protein, a crucial tumor suppressor gene that is frequently mutated in various cancers, including lung cancer. My research focuses on understanding and targeting mutant p53, which behaves differently from the wild-type form and contributes to tumor progression. We have identified a unique sequence that specifically binds to mutant p53, but not to the wild-type protein. Leveraging this specificity, our goal is to develop targeted therapeutic strategies that can selectively recognize and eliminate tumor cells expressing mutant p53. This approach opens new avenues for precision medicine in lung cancer and potentially other p53-mutant cancers.                     

About me: I’m a postdoctoral fellow at Virginia Commonwealth University, deeply passionate about research and discovery. My days are often spent immersed in the lab, where I thrive on solving complex problems and pushing the boundaries of knowledge. When I’m not in the lab, you’ll likely find me on the road—traveling, exploring nature, or experiencing new corners of the world. I have a deep appreciation for different cultures, especially through their food. Cooking is one of my favorite creative outlets, and I love experimenting with cuisines from around the globe. Adventure fuels my spirit. Whether it’s hiking in the mountains, trying something new, or simply wandering off the beaten path, I believe life is meant to be explored — both inside and outside the lab.

Contact: Vidhi.Vashishtha@vcuhealth.org

PI: Devanand Sarkar, Ph.D., Professor

Education:  Ph.D. in Pharmaceutical Sciences, School of Pharmacy, Virginia Commonwealth University (VCU); M.S. in Molecular Biology and Genetics, School of Medicine, VCU; B.Sc. in Genetic Engineering, Faculty of Medical Technology, Derna, Libya

Research: My research focuses on characterizing the gene SLC25A32, also known as the mitochondrial folate transporter, in the context of hepatocellular carcinoma. I am establishing inducible shRNA knockdown clones in HCC cells and generating lentiviruses targeting SLC25A32. Additionally, I am involved in the functional characterization of novel SLC25A32 inhibitors, developed in collaboration with the Medicinal Chemistry team, to investigate their molecular mechanisms of action. This study aims to elucidate the metabolic role of SLC25A32 in hepatocellular carcinoma and explore its potential as a therapeutic target.

About me: When I’m not in the lab, I enjoy cooking and spending time in nature, which helps me recharge and stay creative. My husband and I have a goal of visiting all 50 U.S. states. We’ve already begun exploring nearby places through weekend road trips whenever we get the chance. Traveling offers us a sense of adventure and discovery that brings balance to our busy schedules.

Contact: rabha.younis@vcuhealth.org

PI: Tomasz Kordula, Ph.D., Professor

Education: Ph.D. in developmental and cellular biology

Research: I investigate the role of YY1 deletion in specific subpopulations of cerebellar astrocytes, utilizing innovative subpopulation-specific YY1 conditional knockout (cKO) mouse models. My work also explores chromatin architecture in astrocyte subpopulations at a single-cell resolution.

About me: When I'm not immersed in research, I enjoy spending quality time with my kids.

Contact: masoumeh.zarei@vcuhealth.org